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Microglial calcium signaling is attuned to neuronal

Vladimir V.Senatorov's research works University of

The period following a brain insult like status epilepticus alters neuronal network synchronization, Reference Microglial calcium signaling is attuned to neuronal activity in awake mice.USTC Computational Neuroscience Journal ClubMicroglial calcium signaling is attuned to neuronal activity in awake mice Anthony D Umpierre,Lauren L Bystrom,Yanlu Ying,Yong U Liu,Gregory Worrell,Long-Jun Wu DingTalk APP or 329B 2020/08/07,4:00pm Ping WANGUSTC Computational Neuroscience Journal ClubMicroglial calcium signaling is attuned to neuronal activity in awake mice Anthony D Umpierre,Lauren L Bystrom,Yanlu Ying,Yong U Liu,Gregory Worrell,Long-Jun Wu DingTalk APP or 329B 2020/08/07,4:00pm Ping WANG

Title Postdoctoral Researcher at MayoLocation Rochester,MinnesotaConnections 126Feng Gu's research works Stanford University,CA (SU

The period following a brain insult like status epilepticus alters neuronal network synchronization, Reference Microglial calcium signaling is attuned to neuronal activity in awake mice.Some results are removed in response to a notice of local law requirement.For more information,please see here.Previous123456NextGregory A Worrell's research works Mayo Clinic Microglial calcium signaling is attuned to neuronal activity in awake mice.Article.Full-text available Microglial calcium signaling underlies a number of key physiological and pathological Some results are removed in response to a notice of local law requirement.For more information,please see here.12345NextLatest research,page 24 eLifeAug 04,2020 Microglial calcium signaling is attuned to neuronal#0183;Microglial calcium signaling is attuned to neuronal activity in awake mice Anthony D Umpierre et al.Microglial processes engage calcium signaling in response to hyper- or hypo-active shifts in neuronal activity.

Some results are removed in response to a notice of local law requirement.For more information,please see here.Scientifica - Congratulations to the Wu lab at the Mayo

Microglial processes engage calcium signaling in response to hyper- or hypo-active shifts in neuronal activity.elifesciences Microglial calcium signaling is attuned to neuronal activity in awake miceReview Neuroinflammatory pathways as treatment targets Anthony D Umpierre,Lauren L Bystrom,Yanlu Ying,Yong U Liu,Gregory Worrell,Long-Jun Wu,Microglial calcium signaling is attuned to neuronal activity

Publications Neuroimmune Interaction in Health and Disease

Microglial calcium signaling is attuned to neuronal activity in awake mice.eLife,9 e56502.Chen T,Lennon VA,Liu YU,Bosco DB,Li Y,Yi MH,Zhu J,Wei S,Wu LJ*.2020.Astrocyte-microglia interaction drives evolving neuromyelitis optica lesion.Journal of Clinical Investigation,130(8):4025-4038.Publications - Gregory A.Worrell,M.D.,Ph.D.- Mayo ClinicMicroglial calcium signaling is attuned to neuronal activity in awake mice. Microglial proliferation and monocyte infiltration contribute to microgliosis following status epilepticus. Jobst BC,Khadjevand F,Davis KA,Wanda PA,Kadel A,Rizzuto DS,Kahana MJ.Neural activity reveals interactions between episodic and semantic memory Neuronal Hyperactivity Recruits Microglial Processes via Aug 06,2014 Microglial calcium signaling is attuned to neuronal#0183;Recent studies in the developing zebrafish indicated that microglial responses to laser-induced injury are mediated by calcium signaling acting through NMDA receptors (Sieger et al.,2012) and that uncaged glutamate,acting on neurons,can steer microglial processes toward the site of glutamate release (Li et al.,2012).Our results now provide

Neuronal Calcium Signaling Function and Dysfunction -

Neuronal Calcium Signaling Function and Dysfunction Marisa Brini et al.Cell Mol Life Sci.2014 Aug.Show details Cell Mol Life Sci Actions.Search in PubMed Search in NLM Catalog Add to Search .2014 Aug;71(15):2787-814.doi 10.1007/s00018-013-1550-7.Epub 2014 Jan 19.Neuroimaging Whole-brain imaging reaches new heightsJan 20,2016 Microglial calcium signaling is attuned to neuronal#0183;Microglial calcium signaling underlies a number of key physiological and pathological processes in situ,but has not been studied in vivo in awake mice.Using multiple GCaMP6 variants targeted to microglia,we assessed how microglial calcium signaling responds to alterations in neuronal activity across a wide range.Mobile HomeCage References - NeurotarCalcium signaling; Mitochondrial fragmentation; A.Umpierre,L.L Bystrom,Y.Ying,Y.U.Liu,G.Worrell,L.J.Wu (eLife,2020) Microglial calcium signaling is attuned to neuronal activity in awake mice.DOI 10.7554 In vivo Two-Photon Imaging of Anesthesia-Specific Alterations in Microglial Surveillance and Photodamage-Directed

Microglial calcium signaling is attuned to neuronal

Jul 27,2020 Microglial calcium signaling is attuned to neuronal#0183;However,microglial process calcium signaling is attuned to neuronal activity changes,with both neuronal hypoactivity and hyperactivity triggering increases in microglial process calcium signals.By contrast,microglial somatic calcium changes may represent a disease signature as somatic calcium changes were only evident in longitudinal Microglial calcium signaling in the adult,aged and Microglial calcium signaling in the adult,aged and diseased brain.Brawek B(1),Garaschuk O.Author information (1)Institute of Physiology II,Eberhard Karls University of Tuebingen,Keplerstr.15,72074 Tuebingen,Germany.Microglial cells are the resident immune cells of the CNS.Microglial calcium signaling in the adult,aged and ; Palmer and Gabay,2011 ).

Microglial Remodeling of the Extracellular Matrix Promotes

Jul 23,2020 Microglial calcium signaling is attuned to neuronal#0183;Neuron-Microglial Signaling via IL-33 Drives Experience-Dependent Spine Remodeling To identify cellular targets of IL-33 signaling,we quantified expression of Il1rl1 ,which encodes its obligate co-receptor ( Molofsky et al.,2015 ; Palmer and Gabay,2011 ).Microglia monitor and protect neuronal function through Jan 31,2020 Microglial calcium signaling is attuned to neuronal#0183;Microglia are the main immunocompetent cells of the nervous system and their role in brain development and maintenance of proper neuronal function throughout life is widely recognized (1,2).Changes in microglial activity are linked with major human diseases,including different forms of neurodegeneration,stroke,epilepsy,and psychiatric disorders (3,4).Lab News Neuroimmune Interaction in Health and DiseaseTony's paper entitled Microglial calcium signaling is attuned to neuronal activity in awake mice is published in eLife.Many congrats,Tony! Jul.9,2020.Dr.Long-Jun Wu was invited to serve as an ad hoc reviewer for NIH Fellowships study section (F02B) via Zoom.Jul.2,2020

Frontiers Fractalkine is a find-me signal released by

Apoptotic neurons generated during normal brain development or secondary to pathologic insults are efficiently cleared from the central nervous system.Several soluble factors,including nucleotides,cytokines,and chemokines are released from injured neurons,signaling microglia to find and clear debris.One such chemokine that serves as a neuronalmicroglial communication factor is Choice of cranial window type for in vivo imaging affects Apr 08,2007 Microglial calcium signaling is attuned to neuronal#0183;Additional examples showing microglial activation under open-skull windows,but not thinned skull windows.(PDF 2337 kb) Microglial calcium signaling is attuned to neuronalCell Biology Tree - Long-Jun WuYou can help our author matching system! If you notice any publications incorrectly attributed to this author,please sign in and mark matches as correct or incorrect.Umpierre AD,Bystrom LL,Ying Y,et al.(2020) Microglial calcium signaling is attuned to neuronal activity in awake mice.Elife.9 Wu W,Li Y,Wei Y,et al.(2020) Microglia depletion aggravates the severity of acute and

Author Anthony D.Umpierre,Lauren L.Bystrom,Yanlu Ying,Yong U.Liu,Long-Jun WuPublish Year 2019Microglial calcium signaling is attuned to neuronal

Jul 27,2020 Microglial calcium signaling is attuned to neuronal#0183;An example of breaking down neuronal calcium activity (top) into 3 min bins correlated with changes in microglial calcium activity.Neuronal calcium changes are significant as soon as 15 min after injection.Significant microglial changes are first detected 33 min after injection,suggesting a ~15 min latency between the two.Author Anthony D Umpierre,Lauren L Bystrom,Yanlu Ying,Yong U Liu,Gregory Worrell,Long-Jun WuPublish Year 2020Microglial Calcium Signaling is Attuned to Neuronal Dec 16,2019 Microglial calcium signaling is attuned to neuronal#0183;Microglial calcium signaling underlies a number of key physiological processes in situ ,but has not been studied in vivo in an awake animal where neuronal function is preserved.Using multiple GCaMP6 variants targeted to microglia,we assessed how microglial calcium signaling responds to alterations in neuronal activity across a wide physiological range.Author Anthony D Umpierre,Lauren L Bystrom,Yanlu Ying,Yong U Liu,Gregory Worrell,Long-Jun WuPublish Year 2020(PDF) Microglial Calcium Signaling is Attuned to Neuronal Dec 16,2019 Microglial calcium signaling is attuned to neuronal#0183;Microglial Calcium Signaling is Attuned to Neuronal Activity Anthony D.Umpierre 1 ,Lauren L.Bystrom 1 ,Yanlu Yin g 1 ,Yong U.Liu 1 ,and Long-Jun Wu 1,2,3,4,*

Anthony Umpierre - Postdoctoral Researcher - Mayo Clinic

Microglial calcium signaling is attuned to neuronal activity in awake mice eLIFE Jul 2020.Microglial calcium signaling underlies a number of key physiological processes in situ,but has not been A flexible framework for simulating and fitting Aug 04,2020 Microglial calcium signaling is attuned to neuronal#0183;Microglial calcium signaling underlies a number of key physiological and pathological processes in situ,but has not been studied in vivo in awake mice.Using multiple GCaMP6 variants targeted to microglia,we assessed how microglial calcium signaling responds to alterations in neuronal activity across a wide range.

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